Empowering Exploration into the Next RNA Frontier

High-quality RNA synthesis from 100-300 nucleotides. Designed for purity and performance.

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At Cirena, we’re determined to turn innovations into industry standards. We understand that ordering RNA can be complex. That’s why we’ve made it simple.

Our Promise.

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  • Our chemistry works with numerous modifications including the phosphonoacetate (PACE) modification.

    Examples:

    DNA, 2’O-Methyl, Phosphorothioate (PS), Phosphonoacetate (PACE)

  • We deliver only the highest-purity RNA. All oligos are purified by liquid chromatography (LC) and shipped with mass spectrometry (MS) data. Every oligo meets rigorous analytical standards for identity and quality.

  • We understand that your experiments are waiting. From design to delivery, our streamlined synthesis and purification workflow ensures rapid production without compromising quality. Ready for immediate use in your research.

  • We have been working on this technology for decades. As your project grows, so will we. We offer quantities from microgram to gram scales.

Featured Applications

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Custom long RNAs enable precise control in CRISPR and gene-modification systems. We are excited to aid in the optimization of novel editors. Our PACE modification supports higher editing efficiency and reliable guide RNA performance.

Gene Editing

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Synthetic long RNAs are key for restoring or modulating gene function. We provide high-quality, sequence-verified RNA ideal for therapeutic research and preclinical development.

RNA Replacement Therapeutics

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Our oligos are optimized for folding accuracy and chemical stability, supporting structural and biophysical studies of RNA interactions and small molecule dynamics.

Structural & Folding Studies